Solving Calf Diarrhea:
The Proven Solution Is Here
• Maternal Colostral Immunity Transfer with Sustained High Titers
• 0% Mortality in Challenge Trials and Over 50% Reduction in Scours Duration
ROTAGAL® supplied by Korea Agro Co. Ltd. is an advanced trivalent bovine vaccine providing concurrent protection against Bovine Rotavirus Bovine Coronavirus and enterotoxigenic E. coli (K99). Manufactured by Pharmagal Bio (Slovakia) under strict EU GMP standards it is exported to over 40 countries worldwide including Germany the UK and Australia.
The vaccine is scientifically formulated with TM91 G6P[5] and G6P[1] Rotavirus antigens C-197KWD20 Coronavirus and K99 E. coli antigens. Utilizing the advanced water-in-oil-in-water adjuvant Montanide ISA 206 VG it ensures sustained high neutralizing antibody titers with minimal tissue reaction.
Mechanism and Colostral Protection: When administered to pregnant dams prior to calving ROTAGAL stimulates high concentrations of maternal protective antibodies (IgG) secreted directly into the first colostrum. Newborn calves nursing this colostrum receive immediate robust systemic and mucosal immunity during their most vulnerable first weeks of life.
Academic Challenge Trials (Gyeongsang National University): In rigorous viral and bacterial challenge trials conducted with domestic isolates the non-vaccinated control group suffered 20% to 40% calf mortality. In sharp contrast the ROTAGAL-vaccinated dam group demonstrated 0% mortality. Furthermore diarrhea duration was cut by more than half (1.0–2.5 days vs. 5.5–7.0 days) alongside a 64% reduction in environmental pathogen shedding and verified safety.
